Bradley Smith

Bradley Smith

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Emil T. Hofman, Professor of Chemistry and Biochemistry

Office: 383 Stepan
Phone: 574-631-8632

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Areas of Expertise

  • Smart molecules for imaging
  • Targeting
  • Supramolecular chemistry
  • Bioorganic chemistry
  • Organic synthesis
  • Membrane biophysics
  • Photonics
  • Small animal imaging

Smith is recognized nationally and internationally in the field of supramolecular chemistry applied to biological systems. Within the field of supramolecular chemistry, he is unique in that he designs, synthesizes and studies small organic molecules that affect the dynamic properties of biological membranes. A major aim of his research is to develop novel fluorescent imaging probes that can detect tumors, dying tissue, and bacterial infection in living animals. These imaging probes will accelerate the pre-clinical stages of drug discovery and development and also enable new strategies for studying the biology of human disease. The probes many eventually be employed in humans for fluorescence-guided surgery. Smith currently serves on the editorial advisory boards of the Journal of the American Chemical Society and the Science Advisory Council for Research Corporation.


The transformation of cancer imaging: From shades of gray to living color

1st Source Bank Commercialization Award goes to Mendoza professor Joe Urbany

Notre Dame awards license for Smith’s cell targeting technology

Ten Notre Dame faculty members named AAAS fellows